Role and mechanism of mast cells in solid tumors

Role and mechanism of mast cells in solid tumors

Blog Article

Mast cells are a type of innate immune cells, and have long been considered sofia barclay sexy to be related to the pathogenesis of allergic and autoimmune diseases.However, in recent years, a number of studies have found that mast cells play an indispensable role in tumor development, metastasis, infiltration and angiogenesis, providing new ideas for tumor diagnosis and immunotherapy.Once mast cells have infiltrated solid tumors, they are known as tumor-associated mast cells (TAMCs) and are one of the most controversial immune cells in tumor tissues with remarkable heterogeneity.In view of the important role of mast cells in inflammation and the immune luau thank you cards system, this paper reviews the mechanisms of mast cells in solid tumor development and their relationship with angiogenesis and lymphangiogenesis, aiming to deepen the understanding of the relationship between mast cells and tumors.